EasyFuge is a simple plastic adaptor for use with any standard benchtop centrifuge that enables liquid-suspended cells and particles to be attached to glass for microscopical imaging. It eliminates the need for expensive specialist hardware and, besides being easy to use, EasyFuge’s cell attachment is efficient and allows handling of low volume samples.
Currently, attaching liquid-suspended cells to a microscope slide or coverslip requires expensive, specialised centrifuge instruments. As well as being costly, the process is time consuming, and the equipment requires regular cleaning and maintenance as re-use of attachments needed for these centrifuges can also lead to sample contamination.
Edinburgh’s EasyFuge technology comprises a small, disposable, plastic centrifuge insert into which suspended cells of interest are placed. Cells can then simply and efficiently transferred onto glass using a standard centrifuge, commonly available in most research laboratories. Cleaning and contamination issues are avoided with the low cost, disposable adaptor. This innovative design is suitable for volume samples between 25-150 µ and performs particularly well for 25-50 µ volumes.
Direct comparisons of 3D-printed EasyFuge prototypes have been shown to be as effective at attaching cells to glass as a specialised centrifuge instrument. The EasyFuge devices have been tested using cultured Bone Marrow Macrophage (BMM) cells, fresh primary Buccal Cavity (BC) cells and Jurkat cells at different concentrations and volumes.
Patent application filed
The University of Edinburgh is seeking commercial partners to license this technology and/or collaborate on co-development of the technology for commercial use.
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